Amylase is a digestive enzyme that acts on starch in food, breaking it down into smaller carbohydrate molecules. The enzyme is made in two places. First, salivary glands in your mouth make salivary amylase, which begins the digestive process by breaking down starch when you chew your food, converting it into maltose, a smaller carbohydrate. When starchy foods like rice or potatoes begin to break down in your mouth, you might detect a slightly sweet taste as maltose is released. Cells in your pancreas make another type of amylase, called pancreatic amylase, which passes through a duct to reach your small intestine. Pancreatic amylase completes digestion of carbohydrate, producing glucose, a small molecule that is absorbed into your blood and carried throughout your body.
Primary citation
Structure of human salivary alpha-amylase at 1.6 A resolution: implications for its role in
the oral cavity.
Ramasubbu, N., Paloth, V., Luo,
Y., Brayer, G.D., Levine, M.J.
Journal: (1996) Acta Crystallogr.,Sect.D 52: 435-446
Classification
|
Hydrolase (o Glycosyl)
|
||
Structure Weight
|
56031.33
|
||
Molecule
|
Amylase
|
||
Polymer
|
1
|
Type : protein
|
Length : 496
|
Chains
|
A
|
||
EC#
|
3.2.1.1
|
||
Details
|
Human Salivary Amylase
|
||
Organism
|
Homo sapiens
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Protease
Any enzyme that breaks down protein into its building blocks, amino acids, is called a protease, which is a general term. Your digestive tract produces a number of these enzymes, but the three main proteases are pepsin, trypsin and chymotrypsin. Special cells in your stomach produce an inactive enzyme, pepsinogen, which changes into pepsin when it contacts the acid environment in your stomach. Pepsin breaks certain chemical bonds in proteins, producing smaller molecules called peptides and beginning protein digestion. Your pancreas makes trypsin and chymotrypsin, enzymes that are released into your small intestine through the pancreatic duct. When partially digested food moves from your stomach into your intestine, trypsin and chymotrypsin complete protein digestion, producing simple amino acids that are absorbed into your circulation.
Structure of Protease |
Journal: (2004) Acta Crystallogr.,Sect.D 60: 256-259
PubMed: 14747701
DOI: 10.1107/S090744490302599X
Search Related Articles in PubMed
DOI: 10.1107/S090744490302599X
Search Related Articles in PubMed
PubMed Abstract:
SOURCE FROM rcsb.org
Lipase
Lipase is an enzyme that breaks down dietary fats into smaller molecules called fatty acids and glycerol. A small amount of lipase, called gastric lipase, is made by cells in your stomach. This enzyme specifically digests butter fat in your food. The main source of lipase in your digestive tract is your pancreas, which makes pancreatic lipase that acts in your small intestine. First, bile made in your liver and released into your intestine converts dietary fat into small fatty globules. Pancreatic lipase, also called steapsin, acts on these fat globules, converting them into fatty acids and glycerol, which are small, energy-dense molecules used by all your cells. Fatty acids and glycerol travel in blood and your lymph vessels to reach all parts of your body.
Primary Citation
Crystal structure of Proteus mirabilis lipase, a novel lipase from the Proteus/psychrophilic subfamily of lipase family I.1.
Journal: (2012) Plos One 7: e52890-e52890
PubMed: 23300806
PubMedCentral: PMC3530535
DOI: 10.1371/journal.pone.0052890
Search Related Articles in PubMed
PubMed Abstract:PubMedCentral: PMC3530535
DOI: 10.1371/journal.pone.0052890
Search Related Articles in PubMed
Classification
|
Hydrolase
|
||
Structure Weight
|
34560.21
|
||
Molecule
|
Putative Lipase
|
||
Polymer
|
1
|
Type : protein
|
Length : 307
|
Chains
|
A
|
||
EC#
|
3.1.1.3
|
||
Gene Names
|
PMI0999
|
||
Organism
|
Proteus mirabilis
|
SOURCE FROM rcsb.org
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